CH3 POCl3 pyridine CH2 OH H20 CH3 H3C CH3 Secondary alcohols are often dehydrated in an E2 reaction to give an alkene. Elimination follows Zaitsev's rule to give the more substituted alkene as the major product. Since the reaction occurs via an E2 mechanism, there is no risk of rearrangement of the carbon skeleton as could possibly occur if the elimination occurred via an E1 mechanism with a carbocation intermediate Draw curved arrows to show the movement of electrons in this step of the mechanism. Arrow-pushing Instructions Il CI CH3 HO +CI Cl H3C CH3 Нас CH3 Cl Retry Entire Group 8 more group attempts remaining Submit Answer

CH3 POCl3 pyridine CH2 OH H20 CH3 H3C CH3 Secondary alcohols are often dehydrated in an E2 reaction to give an alkene. Elimination follows Zaitsev's rule to give the more substituted alkene as the major product. Since the reaction occurs via an E2 mechanism, there is no risk of rearrangement of the carbon skeleton as could possibly occur if the elimination occurred via an E1 mechanism with a carbocation intermediate Draw curved arrows to show the movement of electrons in this step of the mechanism. Arrow-pushing Instructions Il CI CH3 HO +CI Cl H3C CH3 Нас CH3 Cl Retry Entire Group 8 more group attempts remaining Submit Answer

Organic Chemistry

9th Edition

ISBN:9781305080485

Author:John E. McMurry

Publisher:John E. McMurry

Chapter17: Alcohols And Phenols

Section17.SE: Something Extra

Problem 71AP: A problem often encountered in the oxidation of primary alcohols to acids is that esters are...

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