Huntington disease is a rare dominant disorder that causes neurodegeneration later in life. In a homozygous state, the dominant allele is lethal.  A man in his thirties, who already has three children, discovers that his mother has Huntington disease though his father is unaffected. What are the following probabilities? a) The man in his thirties will develop Huntington disease. b) His first child will develop Huntington disease. c) Any one out of three of his children will develop Huntington disease.

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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Huntington disease is a rare dominant disorder that causes neurodegeneration later in life. In a homozygous state, the dominant allele is lethal.  A man in his thirties, who already has three children, discovers that his mother has Huntington disease though his father is unaffected. What are the following probabilities?

a) The man in his thirties will develop Huntington disease.

b) His first child will develop Huntington disease.

c) Any one out of three of his children will develop Huntington disease.

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