Some microorganisms have evolved cellular machinery that carries out chemical transformationsin a manner analogous to that of the pyruvate dehydrogenase complex (PDC). One example of theseremarkable transformations is shown below.معلمH3C1. TPP2. lipoamideCH3+3. Coenzyme A H3CHH3CSCOAонProvide a complete curved-arrow mechanism for all three steps of this multistep enzymatic transformation.You may abbreviate the structure of Coenzyme A as "COA-SH" in your mechanism. You do not have to showa mechanism for the regeneration of the lipoamide cofactor.

Approach to solving the question:Identify the key components involved in the enzymatic…

Answered: Some microorganisms have evolved…

Organic Chemistry

8th Edition

ISBN:9781305580350

Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Chapter21: Benzene And The Concept Of Aromaticity

Section: Chapter Questions

Problem 21.63P

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