Which of the following roles is played by the imidazole side chain of His296? Pick the one best [ Select ] answer.

Introduction to General, Organic and Biochemistry
11th Edition
ISBN:9781285869759
Author:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Publisher:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Chapter16: Amines
Section: Chapter Questions
Problem 16.43P
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Here is the same figure as in the previous two questions, but omitting the red circles.
Cys157
Cys157
Cys157
His296
His296
His296
LOH
HN
HN
HN N?
-CO2
CH2
Asn329
Asn329
Asn329-
Cys157
His296
LOH
HN H HyC.
Asn329
Which of the following roles is played by the imidazole side chain of His296? Pick the one best
[ Select ]
answer.
Transcribed Image Text:Here is the same figure as in the previous two questions, but omitting the red circles. Cys157 Cys157 Cys157 His296 His296 His296 LOH HN HN HN N? -CO2 CH2 Asn329 Asn329 Asn329- Cys157 His296 LOH HN H HyC. Asn329 Which of the following roles is played by the imidazole side chain of His296? Pick the one best [ Select ] answer.
V[ Select ]
general base catalysis
general acid catalysis
nucleophilic catalysis
holding the substrate in the active site
Transcribed Image Text:V[ Select ] general base catalysis general acid catalysis nucleophilic catalysis holding the substrate in the active site
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