Which of the following statement is NOT true? O Cell cycle cyclin dependent kinases (CDKs) are synthesized and degraded in every cell cycle O Activity of the S phase CDKs rise in the S phase and drops in the G2 and mitotic phase APC/C proteasome activity increases during mitotic phase and drops towards the end of the G1 phase O G1/S cyclin protein amount rises in the G1 phase

Which of the following statement is NOT true? O Cell cycle cyclin dependent kinases (CDKs) are synthesized and degraded in every cell cycle O Activity of the S phase CDKs rise in the S phase and drops in the G2 and mitotic phase APC/C proteasome activity increases during mitotic phase and drops towards the end of the G1 phase O G1/S cyclin protein amount rises in the G1 phase

Biochemistry

6th Edition

ISBN:9781305577206

Author:Reginald H. Garrett, Charles M. Grisham

Publisher:Reginald H. Garrett, Charles M. Grisham

Chapter28: Dna Metabolism: Replication, Recombination, And Repair

Section: Chapter Questions

Problem 19P: Figure 28.11 depicts the eukaryotic cell cycle. Many cell types â€œexitâ€� the cell cycle and...

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S. Chromosomes are duplicated during what stage of the cell cycle? G1 phase S phase prophase prometaphase
Neurons are arrested in ________ of the cell cycle. a. G1 b. anaphase c. prophase d. S phase
Figure 28.11 depicts the eukaryotic cell cycle. Many cell types â€œexitâ€� the cell cycle and donâ€™t divide for prolonged periods, a state termedG0; some, for example neurons, never divide again. a. In what stage of the cell cycle do you suppose a cell might be when it exits the cell cycle and enters G0? b. The cell cycle is controlled by checkpoints, cyclins, and CDKs. Describe how biochemical events involving cyclins and CDKs might control passage of a dividing cell through the cell cycle.
Which of the following would be expressed at approximately equal levels throughout the cell cycle? O Kinetochore proteins O Cohesins O Cyclins O Cyclin-dependent kinases
Cell cycle checkpoints are surveillance mechanisms that monitor the integrity and fidelity of the major events of the cell cycle. Which of the following are true about cell cycle checkpoints? Select all that apply The M phase checkpoint examines whether all sister chromatids are correctly attached to the spindle microtubules Progression through checkpoints is determined by the activation of cyclin dependent kinases bound to cyclins The G2 checkpoint is also called the restriction checkpoint O If a cell passes the G1 checkpoint, it irreversibly commits to complete the whole cell cycle and divide
Which one of the following statements best describes the mechanism by which the "cell cycle control system" regulates events of the cell cycle? O Hydrophobic signaling molecules cross the plasma membrane at distinct stages in the cell cycle O Ca++ and CAMP release into the nucleus signal the progression of the cell cycle Changes in vesicle trafficking events signal progression of the cell cycle Changes in the cellular cytoskeleton signal progression of the cell cycle Protein phosphorylation and dephosphorylation events signal the progression of the cell cycle
Which of the following statements are correct? Explain your answers. Cells do not pass from G1 into M phase of the cell cycle unless there are sufficient nutrients to complete an entire cell cycle. Apoptosis is mediated by special intracellular proteases, one of which cleaves nuclear lamins. Developing neurons compete for limited amounts of survival factors. Some vertebrate cell-cycle control proteins function when expressed in yeast cells. The enzymatic activity of a CDK protein is determined both by the presence of a bound cyclin and by the phosphorylation state of the CDK.
Which of the following can be correctly deduced from the figure? Gj checkpoint- Souree Jane Reece, et al. Campbell Eiolagy Ninth Edituort. (San Francisco, California Pearson Henjamia The cell cycle control system proceeds on its own, driven by a built-in clock. This control system is subject to internal and external regulation at various checkpoints If a cell receives a go-ahead signal at the G1 checkpoint, the cell continues on in the cell cycle. If a cell does not receive a go-ahead signal at the Gl checkpoint, the cell continues on in cell cycle and goes into Go, a nondividing state. G1 is the restriction point. A. I, II and III B. I, II, and Iv C. I1, III, and IV D. I, II, III, and IV 1. II. III. IV. Which of the following is the correct sequence on the phases of mitosis? A. S-Phase, Metaphase, Interphase, Telophase B. Prophase, Metaphase, Anaphase, Telophase C. Prophase, Metaphase, Interphase, Telophase D. Interphase, Prophase, Metaphase, Telophase Which of the following event…
Which of the following is NOT a checkpoint that controls the progression of cell cycle? The metaphase checkpoint determines if all chromosomes are attached to the spindle apparatus Cytokinesis involves the formation of cleavage furrow to separate the cells The G2 checkpoint checks for DNA damage and determines if all of the DNA is replicated Cyclins and cyclin dependent kinases are protejns that are responsible for advancing a cell through the phases of the cell cycle
Which of the following statements correctly describes how cells progress through the various stages of the cell cycle? Controlled expression and degradation of both cyclins and cdks Controlled expression and degradation of only cyclins Fixed time frame for each phase of the cell cycle independent of protein expression O Controlled expression and degradation of only cdks
Which of the following would result in cell cycle arrest? O phosphorylation of Rb by G1-Cdk phosphorylation of p53 O phosphorylation of helicase by S-Cdk phosphorylation of M-Cdk by CAK phosphorylation of APC by M-Cdk
Degradation of which protein is one of the triggers for the intiation of Mphase of the cell cycle Cyclin A/B Wee1 TOR Cdk1 None of these