The way in which functional chloride channel (CFTR protein) can produce CFTR alleles that cause cystic fibrosis. Introduction: Cystic fibrosis is a genetic disorder that causes severe damage to the lungs, pancreas, digestive system , and other parts of the body. This genetic disorder affects the cells that produce sweat and mucus. In cystic fibrosis, a mutation in a gene changes a protein that controls the movement of salt in and out of cells, resulting in a thick, sticky mucus in the respiratory, reproductive and digestive system as well as increased salt in sweat.

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Definition Definition Organ system that helps in the digestion of food by mechanical and biochemical processes. The digestive system breaks down food into simpler components that enable the body to then absorb or transport nutrients. The human digestive system includes the gastrointestinal tract or alimentary canal and the associate glands. The organs of the gastrointestinal tract include the mouth, pharynx, esophagus, stomach, small intestine, and large intestine. The associated glands include salivary glands, liver, gallbladder, and pancreas.

Chapter 13.4, Problem 1CSC

Summary Introduction

To describe: The way in which functional chloride channel (CFTR protein) can produce CFTR alleles that cause cystic fibrosis.

Introduction: Cystic fibrosis is a genetic disorder that causes severe damage to the lungs, pancreas, digestive system, and other parts of the body. This genetic disorder affects the cells that produce sweat and mucus. In cystic fibrosis, a mutation in a gene changes a protein that controls the movement of salt in and out of cells, resulting in a thick, sticky mucus in the respiratory, reproductive and digestive system as well as increased salt in sweat.

Summary Introduction

To describe: The way in which a gene can affect the timing and rate of transcription and translation.

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The figure below shows the introns and exons found in gene X. The size of each exon and intron is shown as well. A study on this organism found that two mature mRNA molecules are produced for this gene. One is 457 nucleotides in length, and the other is 439 nucleotides in length. Name the process responsible for producing this variation. Also explain how these 457 and 439 nucleotide fragments were produced by referring to the information provided. Hint: This organism produces a poly-A tail of 120 nucleotides.

The figure below shows the introns and exons found in gene X. The size of each exon and intron is shown as well. A study on this organism found that two mature mRNA molecules are produced for this gene. One is 457 nucleotides in length, and the other is 439 nucleotides in length. Name the process responsible for producing this variation. Also explain how these 457 and 439 nucleotide fragments were produced by referring to the information provided. Hint: This organism produces a poly-A tail of 120 nucleotides. 99 62 120 84 102 27 117 Gene X E1 11 E2 12 ЕЗ 13 E4 Exon (E) Intron (I)

The mRNA sequence 5' AUG AAA CAG GGA UAA 3' encodes a particular peptide of interest to your research team. You have identified a new alternate allele of the sequence 5' AUG AAG CAG GGA UAA 3'. What type of mutation does this alternate sequence illustrate?

Answer 2

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Definition Definition Organ system that helps in the digestion of food by mechanical and biochemical processes. The digestive system breaks down food into simpler components that enable the body to then absorb or transport nutrients. The human digestive system includes the gastrointestinal tract or alimentary canal and the associate glands. The organs of the gastrointestinal tract include the mouth, pharynx, esophagus, stomach, small intestine, and large intestine. The associated glands include salivary glands, liver, gallbladder, and pancreas.

Chapter 13.4, Problem 1CSC

Summary Introduction

To describe: The way in which functional chloride channel (CFTR protein) can produce CFTR alleles that cause cystic fibrosis.

Introduction: Cystic fibrosis is a genetic disorder that causes severe damage to the lungs, pancreas, digestive system, and other parts of the body. This genetic disorder affects the cells that produce sweat and mucus. In cystic fibrosis, a mutation in a gene changes a protein that controls the movement of salt in and out of cells, resulting in a thick, sticky mucus in the respiratory, reproductive and digestive system as well as increased salt in sweat.

Summary Introduction

To describe: The way in which a gene can affect the timing and rate of transcription and translation.

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Answer 3

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Definition Definition Organ system that helps in the digestion of food by mechanical and biochemical processes. The digestive system breaks down food into simpler components that enable the body to then absorb or transport nutrients. The human digestive system includes the gastrointestinal tract or alimentary canal and the associate glands. The organs of the gastrointestinal tract include the mouth, pharynx, esophagus, stomach, small intestine, and large intestine. The associated glands include salivary glands, liver, gallbladder, and pancreas.

Chapter 13.4, Problem 1CSC

Summary Introduction

To describe: The way in which functional chloride channel (CFTR protein) can produce CFTR alleles that cause cystic fibrosis.

Introduction: Cystic fibrosis is a genetic disorder that causes severe damage to the lungs, pancreas, digestive system, and other parts of the body. This genetic disorder affects the cells that produce sweat and mucus. In cystic fibrosis, a mutation in a gene changes a protein that controls the movement of salt in and out of cells, resulting in a thick, sticky mucus in the respiratory, reproductive and digestive system as well as increased salt in sweat.

Summary Introduction

To describe: The way in which a gene can affect the timing and rate of transcription and translation.

Expert Solution & Answer

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Answer 4

Question

Definition Definition Organ system that helps in the digestion of food by mechanical and biochemical processes. The digestive system breaks down food into simpler components that enable the body to then absorb or transport nutrients. The human digestive system includes the gastrointestinal tract or alimentary canal and the associate glands. The organs of the gastrointestinal tract include the mouth, pharynx, esophagus, stomach, small intestine, and large intestine. The associated glands include salivary glands, liver, gallbladder, and pancreas.

Chapter 13.4, Problem 1CSC

Summary Introduction

To describe: The way in which functional chloride channel (CFTR protein) can produce CFTR alleles that cause cystic fibrosis.

Introduction: Cystic fibrosis is a genetic disorder that causes severe damage to the lungs, pancreas, digestive system, and other parts of the body. This genetic disorder affects the cells that produce sweat and mucus. In cystic fibrosis, a mutation in a gene changes a protein that controls the movement of salt in and out of cells, resulting in a thick, sticky mucus in the respiratory, reproductive and digestive system as well as increased salt in sweat.

Summary Introduction

To describe: The way in which a gene can affect the timing and rate of transcription and translation.

Expert Solution & Answer

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Answer 5

Chapter 13.4, Problem 1CSC

Summary Introduction

To describe: The way in which functional chloride channel (CFTR protein) can produce CFTR alleles that cause cystic fibrosis.

Introduction: Cystic fibrosis is a genetic disorder that causes severe damage to the lungs, pancreas, digestive system, and other parts of the body. This genetic disorder affects the cells that produce sweat and mucus. In cystic fibrosis, a mutation in a gene changes a protein that controls the movement of salt in and out of cells, resulting in a thick, sticky mucus in the respiratory, reproductive and digestive system as well as increased salt in sweat.

Summary Introduction

To describe: The way in which a gene can affect the timing and rate of transcription and translation.

Answer 6

Chapter 13.4, Problem 1CSC

Summary Introduction

To describe: The way in which functional chloride channel (CFTR protein) can produce CFTR alleles that cause cystic fibrosis.

Introduction: Cystic fibrosis is a genetic disorder that causes severe damage to the lungs, pancreas, digestive system, and other parts of the body. This genetic disorder affects the cells that produce sweat and mucus. In cystic fibrosis, a mutation in a gene changes a protein that controls the movement of salt in and out of cells, resulting in a thick, sticky mucus in the respiratory, reproductive and digestive system as well as increased salt in sweat.

Answer 7

Chapter 13.4, Problem 1CSC

Summary Introduction

To describe: The way in which functional chloride channel (CFTR protein) can produce CFTR alleles that cause cystic fibrosis.

Introduction: Cystic fibrosis is a genetic disorder that causes severe damage to the lungs, pancreas, digestive system, and other parts of the body. This genetic disorder affects the cells that produce sweat and mucus. In cystic fibrosis, a mutation in a gene changes a protein that controls the movement of salt in and out of cells, resulting in a thick, sticky mucus in the respiratory, reproductive and digestive system as well as increased salt in sweat.

Answer 8

Summary Introduction

To describe: The way in which a gene can affect the timing and rate of transcription and translation.

Answer 9

Summary Introduction

To describe: The way in which a gene can affect the timing and rate of transcription and translation.

Answer 10

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Answer 13

Ch. 13.1 - describe three types of RNA that play roles in...Ch. 13.1 - Prob. 2CYL Ch. 13.1 - Prob. 3CYL Ch. 13.2 - Prob. 1TC Ch. 13.2 - Prob. 1CYL Ch. 13.2 - Prob. 2CYL Ch. 13.2 - describe an example of post-transcription...Ch. 13.3 - Prob. 1TC Ch. 13.3 - Prob. 1CSC Ch. 13.3 - Prob. 1CYL

Solution Summary: The author explains cystic fibrosis, a genetic disorder that causes severe damage to the lungs, pancreas, digestive system, and other parts of the body.

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To describe: The way in which a gene can affect the timing and rate of transcription and translation.

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