Biology: The Dynamic Science (MindTap Course List)
4th Edition
ISBN: 9781305389892
Author: Peter J. Russell, Paul E. Hertz, Beverly McMillan
Publisher: Cengage Learning
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Chapter 15.1, Problem 1SB
Summary Introduction
To review:
The reason accounting for the renaming of one gene-one enzyme hypothesis which is based on the work on Neurospora crassa’s auxotrophic mutant, into one gene-one polypeptide hypothesis.
Introduction:
The genes that code for proteins are known as protein-coding genes. The central dogma states that DNA (deoxyribonucleic acid) is converted into RNA (ribonucleic acid), which further produces proteins. The process of the conversion of RNA into proteins is called translation. Beadle and Tatum basically used the genetic approach to study
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A series of auxotrophic mutants were isolated in Neurospora. Examination
of fungi containing these mutations revealed that they grew on minimal
medium to which various compounds (A, B, C, D) were added; growth
responses to each of the four compounds are presented in the following
table. Give the order of compounds A, B, C, and D in a biochemical
pathway. Outline a biochemical pathway that includes these four
compounds and indicate which step in the pathway is affected by each of
the mutations.
Compound
Mutation number
А в С
A
D
134
276
987
773
772
146
333
123
+ + I +
Schizosaccharomyces pombe, also known as "fission yeast," is a powerful model organism in molecular
and cell biology. While performing a genetic screen, you discover an auxotrophic S. pombe strain that
is unable to synthesize one or more vitamins. The following table represents the key experiments you
performed during your genetic screen. Fill in the table with the outcome of each experiment for your
mutant strain (using + for growth and - for no growth).
Medium
Rich media
Minimal media
Minimal media +
all vitamins
Minimal media +
all amino acids
Growth
Wild-type
+
+
+
+
Mutant
+
+
+
>
>
>
The figure below shows the life cycle of the fungus Neurospora. The adult stage of the Neurospora is a multicellular haploid.
b) Neurospora has an arginine amino acid synthesis pathway shown below. Suppose I take the strain above that only grows with arginine supplements and cross it to a different mutant Neurospora strain that grows with arginine and citrulline supplements but not with ornithine supplements. Assuming gens A, B, and C are unlinked and there is only one mutation per stain:
What percentage of the progeny will grow on ornithine?
What percentage on citrulline?
What percentage on arginine?
Chapter 15 Solutions
Biology: The Dynamic Science (MindTap Course List)
Ch. 15.1 - Prob. 1SBCh. 15.1 - If the codon were five bases long, how many...Ch. 15.2 - For the DNA template below, what would be the...Ch. 15.2 - Prob. 2SBCh. 15.3 - Prob. 1SBCh. 15.3 - Prob. 2SBCh. 15.4 - Prob. 1SBCh. 15.4 - Distinguish between the P, A, and E sites of the...Ch. 15.4 - Prob. 3SBCh. 15.5 - How does a missense mutation differ from a silent...
Ch. 15.5 - Prob. 2SBCh. 15.5 - Prob. 3SBCh. 15.5 - Prob. 4SBCh. 15 - Eukaryotic mRNA: usessnRNPs to cut out introns and...Ch. 15 - A segment of a strand of DNA has a base sequence...Ch. 15 - Prob. 3TYKCh. 15 - Prob. 4TYKCh. 15 - Which of the following statements is false? a. GTP...Ch. 15 - Prob. 6TYKCh. 15 - Prob. 7TYKCh. 15 - Prob. 8TYKCh. 15 - Prob. 9TYKCh. 15 - A part of an mRNA molecule with the sequence 5-UGC...Ch. 15 - Discuss Concepts A mutation occurs that alters an...Ch. 15 - Discuss Concepts The normal form of a gene...Ch. 15 - Prob. 13TYKCh. 15 - Prob. 14TYKCh. 15 - Prob. 15TYKCh. 15 - Prob. 16TYKCh. 15 - Prob. 17TYKCh. 15 - Prob. 1ITD
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ISBN:9781305389892
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