Concept explainers
(a)
Interpretation:
The ketone obtained by hydrolysis and decarboxylation of the given
Concept introduction:
The final products of acetoacetic ester synthesis are
(b)
Interpretation:
The ketone obtained by hydrolysis and decarboxylation of the given
Concept introduction:
The final products of acetoacetic ester synthesis are ketones, specially substituted derivatives of acetone. In acetoacetic ester synthesis, substituents are added to the enolate ion of acetoacetic ester. Then, hydrolysis takes place followed by decarboxylation to give alkylated derivatives of acetone.
(c)
Interpretation:
The ketone obtained by hydrolysis and decarboxylation of the given
Concept introduction:
The final products of acetoacetic ester synthesis are ketones, specially substituted derivatives of acetone. In acetoacetic ester synthesis, substituents are added to the enolate ion of acetoacetic ester. Then, hydrolysis takes place followed by decarboxylation to give alkylated derivatives of acetone.
Want to see the full answer?
Check out a sample textbook solutionChapter 22 Solutions
Organic Chemistry (9th Edition)
- How would you synthesize diketones starting from acetoacetic ester?arrow_forwardDraw the product you would expect from the reaction of benzoic acid with 3-methyl-1-butanol. p-toluenesulfonic acid is the catalyst in the reactionsarrow_forwardPropose a reaction for the formation of the following products involving ester formation.arrow_forward
- Draw the products of the following hydrolysis. Н CH2 "CHз О—Н Нзс Нarrow_forward5. Make the following via acetoacetic ester synthesis. شد کاarrow_forwardName the product of the esterification reaction of the two compounds shown here HO, HO O benzyl propanoate O propyl benzoate O benzyl butanoate O butyl benzoatearrow_forward
- describe how steric and electronic effects influence the postion of equilibrium when the electrophilic center of an aldehyde or ketone is under nucleophilic attack.arrow_forwardwhats the product of acid hydrolysis of the following ester with HClarrow_forwardA graduate student was studying enzymatic reductions of cyclohexanones when she encountered some interesting chemistry. When she used an enzyme and NADPH to reduce the following ketone, she was surprised to find that the product was optically active. She carefully repurified the product so that no enzyme, NADPH, or other contaminants were present. Still, the product was optically active. If this reaction could be accomplished using H2 and a nickel catalyst, would the product be optically active? Explain.arrow_forward
- Prepare the following substances from aldehydes or ketonesarrow_forwardDraw the structure of the organic product of the following transformation. Ph3P=CHCO,Et Ph;P=0arrow_forwardWhat is the product of the following reaction, where an ESTER functional group is treated with lithium aluminum hydride?arrow_forward
- Introduction to General, Organic and BiochemistryChemistryISBN:9781285869759Author:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar TorresPublisher:Cengage Learning