BIOLOGY
BIOLOGY
12th Edition
ISBN: 9781260169614
Author: Raven
Publisher: RENT MCG
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Chapter 7, Problem 1DA
Summary Introduction

To describe: The number of ATP molecules that would be produced by the oxidation of fatty acid that has 16 carbons.

Introduction:  The fatty-acid oxidation (β-oxidation) is a metabolic pathway. In this pathway, the fats are metabolized to release energy. The oxidation of fatty acid continually occurs, while it does not become a main source of energy until the animals’ carbohydrate resources are exhausted. The oxidation of fatty acid mainly occurs in peroxisomes in plant cells and mitochondria in animal cells.

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During the catabolism of fats, one molecule of ATP is used in each round of beta-oxidation and produces one molecule each of NADH and FADH2. Seven rounds of beta-oxidation would convert the fatty acid into eight molecules of acetyl-CoA for a 16-carbon fatty acid. In the Krebs cycle, the oxidation of each acetyl-CoA produced 10 molecules of ATP.

Thus, the overall yield of ATP from 16-carbon fatty acid would be a net gain of 21 ATP from seven rounds of beta-oxidation (gain of 4 ATP per round – 1 per round of prime reaction) + 80 ATP from the oxidation of 8 acetyl-CoA = 101 ATP molecules.

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