Biology (MindTap Course List)
11th Edition
ISBN: 9781337392938
Author: Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg
Publisher: Cengage Learning
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Chapter 8, Problem 3TYU
Before pyruvate enters the citric acid cycle, it is decarboxylated, oxidized, and combined with coenzyme A, forming acetyl CoA, carbon dioxide, and one molecule of (a) NADH (b) FADH2 (c) ATP (d) ADP (e) C6H12O6
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Outline the conditions that direct pyruvate toward the following:(a) Entry into the citric acid cycle(b) Conversion to ethanol and CO2(c) Conversion to lactate(d) Glucose synthesis (gluconeogenesis)In what tissues or organisms is each pathway present?
The two main goals of the citric acid cycle are:
(a) citrate synthesis and gluconeogenesis
(b).degradation of acetyl-CoA to produce energy and supply precursors for anabolism
(c).degradation of pyruvate to produce energy and supply precursors for anabolism
(d).degradation of glucose to produce energy and supply precursors for anabolism
(e).degradation of pyruvate to produce energy and synthesize oxaloacetate for gluconeogenesis
Before pyruvate enters the citric acid cycle, it is decarboxylated, oxidized, and combined with coenzyme A, forming acetyl CoA, carbon dioxide, and one molecule of (a) NADH (b) FADH2 (c) ATP (d) ADP (e) C6H12O6
Chapter 8 Solutions
Biology (MindTap Course List)
Ch. 8.1 - Write a summary reaction for aerobic respiration...Ch. 8.1 - Prob. 1CCh. 8.1 - Prob. 2CCh. 8.2 - Prob. 2LOCh. 8.2 - Prob. 3LOCh. 8.2 - Add up the energy captured (as ATP, NADH, and...Ch. 8.2 - Prob. 5LOCh. 8.2 - Prob. 6LOCh. 8.2 - Prob. 1CCh. 8.2 - Prob. 2C
Ch. 8.2 - What are the roles of NAD+, FAD, and oxygen in...Ch. 8.2 - Prob. 4CCh. 8.3 - Summarize how the products of protein and lipid...Ch. 8.3 - Prob. 1CCh. 8.3 - Prob. 2CCh. 8.3 - Prob. 3CCh. 8.4 - Compare and contrast anaerobic respiration and...Ch. 8.4 - What is the fate of hydrogen atoms removed from...Ch. 8.4 - What accounts for the ATP yield of fermentation...Ch. 8.4 - Is chemiosmosis involved in fermentation? in...Ch. 8 - A chemical process during which a substance gains...Ch. 8 - The reactions of _____ take place within the...Ch. 8 - Before pyruvate enters the citric acid cycle, it...Ch. 8 - In the first step of the citric acid cycle, an...Ch. 8 - Which of the following is the major source of...Ch. 8 - The aerobic part of aerobic cellular respiration...Ch. 8 - Prob. 7TYUCh. 8 - A net profit of only 2 ATPs can be produced...Ch. 8 - When deprived of oxygen, yeast cells obtain energy...Ch. 8 - Which of the following is a correct ranking of...Ch. 8 - Prob. 11TYUCh. 8 - CONNECT Explain why the proton gradient formed...Ch. 8 - CONNECT How are the endergonic reactions of the...Ch. 8 - PREDICT Could the inner mitochondrial membrane...Ch. 8 - Prob. 15TYUCh. 8 - Prob. 16TYUCh. 8 - EVOLUTION LINK The reactions of glycolysis are...Ch. 8 - Prob. 18TYU
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- The citric acid cycle converts each acetyl-CoA to [1/2/3/4] molecules of CO2. This pathway is considered [catabolic/anabolic] because it breaks down acetyl-CoA into smaller molecules and [catabolic/anabolic] because the intermediates are building blocks for other metabolites in the cell. The citric acid cycle produces [1/2/3] NADH and [1/2/3] FADH2 for every acetyl-CoA consumed. help fill in the blanksarrow_forwardMany amino acids are broken down to intermediates of the citric acid cycle. (a) Why can’t these amino acid “remnants” be directly oxidized to CO2 by the citric acid cycle? (b) Explain why amino acids that are broken down to pyruvate can be completely oxidized by the citric acid cycle.arrow_forwardIn the first step of the citric acid cycle, an acetyl group from acetyl CoA reacts with oxaloacetate to form (a) pyruvate (b) citrate (c) NADH (d) ATP (e) CO2arrow_forward
- The citric acid cycle is a critical sequence of reactions for energy production, which take place in the matrix of the mitochondria. The reaction cycle requires materials from the cytosol to be converted into acetyl CoA, which represents the starting point of a new cycle. Which of the following statements about acetyl CoA is true? (a) Acetyl CoA is recycled at the end of every cycle. (b) Oxaloacetate is attached to acetyl CoA to feed the citric acid cycle. (c) Triacylglycerol molecules are transported into the mitochondrial matrix and cleaved by lipases to produce acetyl CoA. (d) Oxaloacetate is converted directly into acetyl CoA to feed the citric acid cyclearrow_forwardHow does each of the following regulate citric acid cycle?(a) High levels of Succinyl-CoA(b) High levels of ADP(c) High levels of NADHarrow_forwardThe CO2 produced in one round of the citric acid cycle does not originate in the acetyl carbons that entered that round. (a) How many rounds are required before 14CO2 is released if acetyl-CoA is labeled at its methyl group? (b) If acetyl-CoA is labeled with 14C at its carbonyl carbon, how many rounds of the cycle are required before 14CO2 is released?arrow_forward
- Tomorrow morning, you decide to sprint a quick mile before breakfast. Which enzymes will be actively metabolizing fuel in your myocytes during the sprint? Choose ALL that apply. (A) acetyl CoA carboxylase 1(B) fructose 1,6 bisphosphatase (C) glycogen phosphorylase(D) HMG-CoA reductase(E) a-ketoglutarate dehydrogenase (F) lactate dehydrogenase(G) mitochondrial b-ketothiolase (H) phosphofructokinase 1arrow_forwardWhich glycolysis reactions are catalyzed by the following enzymes?(a) Pyruvate kinase(b) Glyceraldehyde 3-phosphate dehydrogenase(c) Hexokinase(d) Phosphoglycerate mutase(e) Aldolasearrow_forwardWhich of the following is the sixth step of Citric Acid Cycle? Select one: a. Succinate is oxidized to become fumarate forming FADH2 b. alpha-ketoglutarate is oxidized and decarboxylated to produce Succinyl-CoA, Carbon dioxide and NADH c. Isocitrate and then decarboxylated and oxidized to produce alpha-ketoglutarate, Carbon dioxide and NADH d. Oxaloacetate combines with the acetyl from acetyl-CoA to produce Citric acid(citrate) e. Malate is oxidized to become oxaloacetate forming NADH f. Fumarate is combined with water to become Malate g. Citrate is rearranged to become Isocitrate h. Pyruvate is decarboxylated to become acetyl-CoA producing NADH and Carbon dioxide i. Succinyl-CoA becomes Succinate and forms one ATP molecule and Coenzyme A-SHarrow_forward
- The pathway that converts glucose to acetyl-CoA is often referred to as an “aerobic oxidation pathway.” (a) Is molecular boxygen involved in any of the steps of glycolysis? (b) Thinking back to Chapter 20, where does molecular oxygen enter the picture?arrow_forwardWhich of the following is the second step of Citric Acid Cycle? Select one: a. Isocitrate and then decarboxylated and oxidized to produce alpha-ketoglutarate, Carbon dioxide and NADH b. Succinyl-CoA becomes Succinate and forms one ATP molecule and Coenzyme A-SH c. alpha-ketoglutarate is oxidized and decarboxylated to produce Succinyl-CoA, Carbon dioxide and NADH d. Malate is oxidized to become oxaloacetate forming NADH e. Fumarate is combined with water to become Malate f. Citrate is rearranged to become Isocitrate g. Pyruvate is decarboxylated to become acetyl-CoA producing NADH and Carbon dioxide h. Oxaloacetate combines with the acetyl from acetyl-CoA to produce Citric acid(citrate) i. Succinate is oxidized to become fumarate forming FADH2arrow_forwardWhich of the following statements about the pentose phosphate pathway (PPP) is true? (A) The purpose of the pentose phosphate pathway is to produce NADH for use in anabolic pathways and ribose 6-phosphate for nucleotide synthesis.(B) The oxidative arm of the PPP produces (2) NADPH per glucose 6-phosphate that enters the pathway. (C) Phosphopentose isomerase converts the ribose 5-phosphate made in the oxidative arm of the PPP into ribulose 5-phosphate that is used to form the ribose sugar of nucleotides.(D) The non-oxidative arm of the PPP interconverts between ribose 5-phosphate and a variety of intermediates of b-oxidation. (E) One of the functions of the PPP is to provide NADPH that inhibits glutathione reductase so that it cannot oxidatively damage RBCs.arrow_forward
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