Genetics: Analysis and Principles
6th Edition
ISBN: 9781259616020
Author: Robert J. Brooker Professor Dr.
Publisher: McGraw-Hill Education
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Chapter 8.6, Problem 1COMQ
Summary Introduction
Introduction:
Down syndrome, also called Trisomy 21 is a type of genetic disorder in which trisomy of chromosome 21 in an individual occurs. It is one of the most prominent and commonly occuring genetic disorders found in humans. Patients of Down syndrome have physical, intellectual, and mental problems.
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Fragile X is a disorder which causes mental impairment in affected individuals. The trait which is due to a mutation in the FMR1 gene on the X chromosome is inherited in a recessive manner. An unaffected son was born to an affected man and an unaffected woman. The woman’s mother was affected while the father was normal. a. Indicate the gene notation. b. Give the genotype of the son. c. Is it possible for the couple to have an affected daughter? affected son? Derive the genotypic and phenotypic ratios for the offspring. Show and label your solutions properly. d. If the couple has four children, what is the probability that they will have three normal daughters and one normal son?
In an organism’s genome, autosomes are
a. the chromosomes that differ between the sexes.
b. chromosomes that are involved in sex determination.
c. only inherited from the mother (maternal inheritance).
d. all of the chromosomes other than sex chromosomes
If a Drosophila female that is homozygous for an X-linked recessive mutation is bred with a male that carries the corresponding wild-type allele, the offspring will.....
a. show the mutant phenotype in all individuals.
b. be uniform wild-type.
c. show a phenotype intermediate to the parents' phenotype.
d. show the mutant phenotype in all males and the wild-type phenotype in all females.
e. have mutant and wild-type males and mutant and wild-type females.
Chapter 8 Solutions
Genetics: Analysis and Principles
Ch. 8.1 - 1. A chromosome that is metacentric has its...Ch. 8.1 - Staining eukaryotic chromosomes is useful because...Ch. 8.2 - Prob. 1COMQCh. 8.3 - Which of the following statements is correct? a....Ch. 8.3 - Prob. 2COMQCh. 8.4 - 1. A paracentric inversion
a. includes the...Ch. 8.4 - Due to crossing over within an inversion loop, a...Ch. 8.4 - 3. A mechanism that may cause a translocation is...Ch. 8.5 - 1. Humans have 23 chromosomes per set. A person...Ch. 8.6 - Prob. 1COMQ
Ch. 8.6 - Prob. 2COMQCh. 8.7 - The term endopolyploidy refers to the phenomenon...Ch. 8.7 - 2. In agriculture, an advantage of triploidy in...Ch. 8.8 - Prob. 1COMQCh. 8.8 - The somatic cells of an allotetraploid contain a....Ch. 8 - 1. Which changes in chromosome structure cause a...Ch. 8 - Prob. 2CONQCh. 8 - 3. How does a chromosomal duplication occur?
Ch. 8 - 4. What is a gene family? How are gene families...Ch. 8 - Prob. 5CONQCh. 8 - Two chromosomes have the following orders for...Ch. 8 - An inversion heterozygote has the following...Ch. 8 - Prob. 8CONQCh. 8 - Explain why inversions and reciprocal...Ch. 8 - 10. An individual has the following reciprocal...Ch. 8 - A phenotypically normal individual has the...Ch. 8 - 12. Two phenotypically normal parents produce a...Ch. 8 - With regard to the segregation of centromeres, why...Ch. 8 - Prob. 14CONQCh. 8 - Prob. 15CONQCh. 8 - 16. A phenotypically abnormal individual has a...Ch. 8 - 17. A diploid fruit fly has eight chromosomes. How...Ch. 8 - Prob. 18CONQCh. 8 - Prob. 19CONQCh. 8 - 20. Aneuploidy is typically detrimental, whereas...Ch. 8 - 21. Explain how aneuploidy, deletions, and...Ch. 8 - Prob. 22CONQCh. 8 - 23. A cytogeneticist has collected tissue samples...Ch. 8 - Prob. 24CONQCh. 8 - A zookeeper has collected a male and a female...Ch. 8 - Prob. 26CONQCh. 8 - 27. What is mosaicism? How is it produced?
Ch. 8 - 28. Explain how polytene chromosomes of Drosophila...Ch. 8 - 29. Describe some of the advantages of polyploid...Ch. 8 - 30. While conducting field studies on a chain of...Ch. 8 - Prob. 31CONQCh. 8 - Which of the following terms should not be used to...Ch. 8 - Prob. 33CONQCh. 8 - Prob. 34CONQCh. 8 - A triploid plant has 18 chromosomes (i.e., 6...Ch. 8 - Prob. 36CONQCh. 8 - Prob. 37CONQCh. 8 - 38. A woman who is heterozygous, Bb, has brown...Ch. 8 - 39. What is an allodiploid? What factor determines...Ch. 8 - Prob. 40CONQCh. 8 - 41. Table 8.1 shows that Turner syndrome occurs...Ch. 8 - 42. Male honeybees, which are haploid, produce...Ch. 8 - Prob. 1EQCh. 8 - Prob. 2EQCh. 8 - With regard to the analysis of chromosome...Ch. 8 - 4. Describe how colchicine can be used to alter...Ch. 8 - 5. Describe the steps you would take to produce a...Ch. 8 - Prob. 6EQCh. 8 - What are G bands? Discuss how G bands are useful...Ch. 8 - A female fruit fly has one normal X chromosome and...Ch. 8 - Prob. 2QSDCCh. 8 - Besides the ones mentioned in this textbook, look...Ch. 8 - Prob. 4QSDCCh. 8 - 5. Discuss the importance of gene families at the...
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- Red–green color blindness in humans is due to an X-linked recessive gene. A woman whose father is color blind possesses one eye with normal color vision and one eye with color blindness. a. Propose an explanation for this woman’s vision pattern. Assume that no new mutations have spontaneously arisen. b. Would it be possible for a man to have one eye with normal color vision and one eye with color blindness?arrow_forwardWhich of the following is associated with chemical modifications to chromosomes that label alleles as coming from the mother or father? a. Multiple alleles b. Extranuclear inheritance c. Epigenetic marks d. Small non coding RNAsarrow_forwardWhich of the following situations does not describes a chromosomal mutation? Select one: a. A cytosine nucleotide is substituted for thymine nucleotide in a gene. b. A portion of Chromosome 4 is deleted during interphase of meiosis. c. The sister chromatids of Chromosome 18 do not separate during anaphase II. d. A section of Chromosome 17 is duplicated leading to problems in the peripheral nervous system.arrow_forward
- Which of the following statements is FALSE? Inactivation of one of the two X chromosomes in the somatic cells of mammalian females..... a. underlies the Calico phenotype in cats. b. leads to cellular mosaicism in females heterozygous for an X-linked gene. c. affects 75 % of the paternal and 25 % of the maternal X-chromosomes of a mammalian body. d. leads to the formation of a Barr body in female cells' nuclei. e. is the mechanism in mammals to compensate for the higher dosage of X-linked genes in females as compared to males.arrow_forwardCan chromosome duplications cause negative effects to an organism? Why or why not? A. No. Duplicated regions of chromosomes are quickly lost by looping out during meiosis. B. Yes. Duplicated regions increase gene dosage, which affects processes like development that require specific amounts of protein. C. No. Cells with duplications function even more efficiently than those without duplications. D. No. Duplicated regions of chromosomes cannot affect gene dosage because the cell can always compensate for extra copies of genes. E. Yes. Duplicated regions require DNA to be replicated, which delays the cell cycle and wastes energy.arrow_forwardChromosome translocations include: A. Alterations in which the genetic material remains the same but rearranged B. Alterations in which the total amount of genetics information increases C. Alterations in which the total amount of genetics information decreases D. Variations in the chromosome numberarrow_forward
- Which of the below explains why trisomy is better tolerated in humans than monosomy? (Select all correct options). a. Loss of heterozygosity in monosomy b. Increased gene expression in trisomic cells is beneficial c. Reduced gene expression in monosomy d.The extra chromosome in trisomic cells is degraded Which two are both necessary to hold a tetrad together until Anaphase I? a) nondisjunction b) cross over c) centromere cohesion d) synaptonemal complex e) separese activityarrow_forwardCategorize each of the following events as an example of genetic inheritance or epigeneticinheritance. a. For a line of liver cells growing in a laboratory, a gene encoding an immune cytokine isfound in compact chromatin.b. A chromosomal rearrangement in a blood stem cell leads to leukemia.c. Haploid bees are male, and diploid bees are female.d. Among genetically identical lab mice, those exposed to cigarette smoke have a higherrate of developing lung tumorsarrow_forwardWhich of the following statements is FALSE about x chromosome inavtivation in mammals? A. It relies on chromatic remodeling B. It leads to the formation of Barr body. C. It only occurs in males. D. It involves histone modificationarrow_forward
- For items 1-10, refer to the choices below: a. Williams Syndrome b. Cri-Du-Chat Syndrome c. Pallister-Killian Syndrome d. Wolf-Hirschhorn Syndrome 1. Caused by a deletion in chromosome 5. 2. Has bulging, wide-set eyes. 3. Has hypertelorism. 4. Caused by an isochromosome. 5. Caused by the deletion of multiple genes on chromosome 7. 6. About 30% of the people with this disorder are autistic. 7. They have an elf-like face. 8. Has a high chance of having scoliosis. 9. White starburst pattern around the irisarrow_forwardIn mammals, males have X and Y sex chromosomes, while females have two Xs. While the Y sex chromosome has very few genes associated with it, the X sex chromosome has many that are important to maintain life. How do mammals account for this in terms of equaling out gene expression levels? A. Mammals do not need to account for this, but birds do. B. Females produce more proteins from X-linked genes than males do. C. The single X of the males works twice as hard to keep up with the female’s two Xs. D. The females have one X inactivated to permit the males to keep pace with them.arrow_forwardWhich of the following disorders in humans has an X-linked recessive inheritance pattern? a.Hutchinson-Gilford progeria b.Tay-Sachs disease c.Marfan syndrome d.Red-green color blindness Which of the following is described as a structural rearrangement of a chromosome in which a broken piece has become reattached in the wrong location? a.Duplication b.Translocation c.Inversion d.Deletion Which of the following disorders arises from translocation events? a.Huntington’s disease b.Infertility c.Burkitt lymphoma d.Duchenne muscular dystrophyarrow_forward
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