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- Question 19 A transversion mutation would be replacing T by: A either A or G BU (c) T D) cQuestion 47 (a) Use the following figure to determine the changes to the amino acids that correspond to the normal and mutated DNA sequences. Normal DNA sequence: 3 CAT TCA AAC ATT 5 Mutated DNA sequence: 3 CAT AGT GAG GTC 5 (Hint: Write the mRNA first, then identify the amino acids.) (b) What type of mutation is shown? First base of codon U C A G U UUU UUC UUA UUG CUU CUC CUA CUG AUU AUC AUA AUG GUU GUC GUA GUG UCU UCC UCA UCG CCU CCC CCA CCG ACU ACC ACA Met ACG GCU GCC GCA GCG Phe -Leu Leu lle Second base of codon A C Val -Ser Pro Thr Ala UAUTYT туг UAC UAA UAG CAU CAC CAA CAG. His Gin AAU AAC Asn AAA GAUT GAC GAA GAG Asp G AAGLYS AGG. GGU GGC GGA GGG Glu UGU UGC UGA UGG CGU CGC CGA CGG Bys A Trp G U C -Arg AGU AGC AGA аса за Ser Arg U C Gly AG A U C A G U C A G Third base of codonQuestion 7 A unique 5'CCA terminal sequence is found in all RNAS to be able to carry the correct amino acid to the ribosome. A True B) False
- QUESTION 25 What is the most common type of DNA sequence present in eukaryotic genomes? A. Repetitive DNA sequences B. Minisatellites C. Exons of genes encoding proteins D. Introns of genes encoding proteinsQuestion 18 Match Column A with Column B. transports amino acids to the site of protein synthesis A. operator B. rRNA has anticodon loop C. IRNA v directs amino acid sequence of proteins D. MRNA contains the Shine-Delgarno sequence E. most type of RNA v synthesized in the eukaryote nucleus F. promoter v found inside the ribosome v region where the RNA binds to the DNA template region where the activator protein binds to the DNA templateQuestion 17 What is the nucleotide sequence of the DNA strand that is complementary to 5'-ATCGCAACTGTCACTA-3 A 5'-UAGUGACAGUUGCGAU-3' B 5-TAGCGTTGACAGTGATA-3 5'-ATCACTGTCAACGCTA-3 D 5'-TAGTGACAGTTGCGAT-3'
- Question 22 Which type of mutation results in no change in amino acid sequence for the protein? a Silent b Missense c Nonsense d FrameshiftQuestion 33 Given the electrophoresis profile of a Sanger sequencing result, what was the sequence of the original DNA sample used for sequencing? ddATP ddGTP ddCTP ddTTP A) GGTAACC в) ССААТGG GGTTACC D) CCATTGG | | | |QUESTION 21 Choose each of the characteristic(s) of all RNA polymerases from the list below. A. elongation adds new ribonucleotides to the 3-OH B. requires a primer to initiate synthesis C. have 3' to 5' exonuclease activity D. adds nucleotides based on sequence complementarity to a template E. have 5' to 3' polymerase activity O F. elongation adds new ribonucleotides to the 2'-OH G. have 3' to 5' polymerase activity
- Question 6 1 pts You are assembling the genome sequence of a newly discovered bacterium by aligning a set of BAC clones. Correct assembly requires O spacer regions O repeated sequences O overlapping sequencesQuestion 14 During RNA chain elongation gyrase proceeds ahead of the transcription bubble in order to A remove positive supercoils by a cut and seal process B remove positive supercoils by creating relaxed DNA c remove negative supercoils by removing H-bonds D) remove negative supercoils by unwinding the 2 strandsQuestion 46 Cellular transcription is : O Use of DNA as a template to make complementary DNA Use of DNA as a template to make complementary RNA O Use of RNA as a template to make proteins