X' enzyme *NH3 PLP *NH3

Q: Fractional analysis, methylation, and periodate oxidation…

A: 1. Fractional analysis, methylation, and periodate oxidation is the chemical method which identify…

Q: Triethylenemelamine (TEM) is an antitumor agent. Its activity is due to its ability to cross-link…

A: (a) The triethylenemelamine (TEM) is an alkylating agent whoes main power lies in the triple three…

Q: The rate constant for the uncatalyzed reaction of two molecules of glycine ethyl ester to form…

A:

Q: Complete Reaction NBS (N B1omo Succinamide) DCM (CHCI,) dchlore methone

A: Introduction: Addition reaction is a reaction in which substituent get attached to double bond to…

Q: Draw the electron pushing reaction mechanism for the hydrolysis of the artificial sweetener…

A: Aspartame on hydrolysis gives aspartic acid, phenyl alanine and methanol under acidic, basic and…

Q: The given compound contains no alpha hydrogens.Will it undergo cannizarro reaction(including…

A: Answer: Cannizzaro reactions are those which takes place when two molecules of an aldehydic group…

Q: 16) Propose a mechanism for how iron(III) chloride could inhibit the peroxidase enzyme on a…

A:

Q: Identify an example of initiation. A) homolytic cleavage B) heterolytic cleavage hydrogen…

A: We know that  Initiation  reaction :   initiation step is a reaction in which radicals are formed…

Q: Dehydratase is a PLP-requiring enzyme that catalyzes an a,ß-elimination reaction. Propose a…

A:

Q: Explain the mechanism for acid-catalyzed transesterification.

A: Transesterification is the reaction of the exchange of organic groups between ester and alcohol to…

Q: The macrolide shown below is the core of the antibiotic tiacumicin. Draw the primer and the…

A:

Q: The reaction HCl(aq) + H₂O(l) --> H3O*(aq) + Cl¯(aq) is an example of: homolytic cleavage by proton…

A: Given: HCl(aq) + H₂O(I) --> H3O+ (aq) + Cl¯(aq) To identify:  This reaction is an example of…

Q: Dehydratase is a PLP-requiring enzyme that catalyzes an α,β-elimination reaction. Propose a…

A: An alpha, beta-elimination reaction is catalyzed by dehydratase, a PLP requiring enzyme. The given…

Q: MCPBA МеMgBr (excess), н- Swern a) b) c) оxidation

A:

Q: The enzyme that catalyzes the Ca ¬ Cb bond cleavage reaction that converts serine to glycine removes…

A:

Q: -CO̟Et OAc -co,Et OCH3 (i) dil aq. HCI, 70 °C Lipase PS, t-BUOCH3, 168 h OH он (S)-2 (iї) K-СОз, 168…

A: We have to identify the new signal(s) in compound 3 would you expect not to be in (R/S)-2 for H NMR…

Q: H2 + CH2 = CH2 --> CH3CH3 Which of the following could be a substrate for an enzyme that has an…

A: Option D is Correct Answer.

Q: (-)-Ipc2BOTf i-Pr2NEt ЗА CH2CI2, -20 oC TBSOTF 2,6-lutidine 4B 50 CH2CI2, -78 °C structure of 3A?…

A: The geometry of enolate depends on the chiral borate reagents. (-)Ipc2BOTf majorly produces…

Q: The following three derivatives of succinimide are anticonvulsants that have found use in the…

A:

Q: When some sugars dissolve in water they spontaneously undergo changes in optical rotation called…

A:

Q: In the figure below, His carries out generates| tetrahedral intermediate is stabilized by the by…

A: In the given figure, the lone pair of electron on the nitrogen of Histidine residue is donated to…

Q: H3C CH3 H3C CH3 NaN3 NaCI H3C CI H3C "N3

A: Here we have to write structure of initially formed tetrahedral intermediate formed when…

Q: Give an example of each of the following: a) Heterolytic cleavage by hydride transfer. b) Homolytic…

A: a) Heterolytic cleavage by hydride transfer: The heterolytic cleavage indicates the breaking of bond…

Q: 5. Among many of the drugs studied for the treatment of cancer is the carboxamide derivative Poly…

A: Major product.

Q: Candoxatrilat is a potent neutral endopeptidase (NEP) inhibitor. Researchers designed multiple…

A:

Q: Show the mechanism for the acid-catalyzed formation of 23c starting with the product obtained from…

A: Fischer esterification- When carboxylic acid is heated with alcohol in presence of concentrated…

Q: Provide a multistep synthesis.

A: The above transformation involves reduction of ester to form aldehyde, methylation at alpha position…

Q: 7- Uricase acts on uric acid to produce allantoin, carbon dioxide andhydrogen peroxide. Hydrogen…

A: We are allowed to solve only one question per session , so i am solving 7th question , please ask…

Q: The enzyme that catalyzes the C-Cg bond cleavage reaction that converts serine to glycine removes…

A: The chemical structure for PLP, serine, and glycine is shown below.

Q: In the Friedel-Crafts acylation (acid chloride), which of the following can serve as the active…

A: The question is based on the concept of organic reactions. we have to identify the correct…

Q: Proindetie Product CN CN NacN DMSO horcachion

A: Nucleophilic substitution occurs when the leaving group is good.

Q: Show a reasonable mechanism for the enzymatic transimination reaction 6. : between the PLP-lysine…

A: The transimination, just like transamination, is a biochemical reaction in which an imino group is…

Q: Propose a mechanism for the formation of Melmac.

A: Melmac is a polymer which is formed by the polymerisation of monomers melamine and CH2O

Q: Sterol Biosynthesis A) Name the enzymes and draw the reactions for the synthesis of lanosterol from…

A: Sterols are vital components of all eukaryotic cell membranes, and are essential for cell growth and…

Q: Select the final major produt of the following reactian sequence: 1C mgBr, EtD CrOg -> 2. H30* NAOH…

A:

Q: Cyclic peptides received increasing amounts of attention because of their pharmaceutical propertie…

A: Cyclic peptides have much importance in Pharmaceutical industries. This cyclic peptides are formed…

Q: (b) Provide a mechanism for the coupling of Boc-Gly-OH with H-Phe- O'Bu using EDCI, DMAP and Hünig's…

A: Carboxylic acid react with EDCl DMAP react with product of carboxylic acid of EDCl Nucleophilic of…

Q: The following compound has been found to be an inhibitor of penicillinase. The enzyme can be…

A: Penicillinase is an enzyme that provides resistance to penicillin by using CH2OH group to open the…

Q: 1. Enz-0-H opo3 Enz, Draw a mechanism for the below, which involves twa steps and the starting point…

A: To draw a mechanism for the below, which involves two steps and the starting point of the enzyme (on…

Q: There are two kinds of aldolases. Class I aldolases are found in animals and plants, whereas class…

A: solution- Aldolases are often used to convert  glyceraldehyde 3-phosphate. After bringing about this…

Q: v 12.75a Of the following, which represents a logical retrosynthesis for target molecule A? MgBr OH…

A:

Q: In this reaction, D‑erthyro‑imidazole‑glycerol phosphate is first protonated to form a good leaving…

A:

Q: Ме MegPl.Rh-PMe3+ CO2 A Insertion MegP PMe3

A: Mechanism of CO2 insertion:  Rh(PMe3)4(Me) + CO2 -------- Rh(OCOMe)(PMe3)4

Q: 3. The following sequence comes from a synthesis of strychnine. Fill in the reagents to complete the…

A:

Q: NaOEt, EtOH A 1.ВН, ? 2. H202 OH SOCI2, piridin В (А) ISI IOH

A:

Q: Identify an example of termination. A homolytic cleavage B heterolytic cleavage C) hydrogen…

A: The options given are homolytic cleavage, heterolytic cleavage, hydrogen abstraction, coupling and…

Q: Identify the overlapping orbitals involved in the formation of each numbered bond.

A: Here we are given two molecules and in this we are mentioned 7 type of bonds and we have to write…

Designing a Synthesis

Organic synthesis is a branch of chemical synthesis that involves the planned construction of organic compounds/molecules from smaller units that possess functional groups. Friedrich Wöhler was the first scientist who designed the synthesis of an organic compound, urea from inorganic starting materials silver cyanate with ammonium chloride via a simple, one-step synthesis.