Propose a retrosynthesis for Spliceostatin A shown.

Q: The distance between the porphyrin plane and proximal histidine is longer in T-state than that in…

A: Answer- In Tensed state iron exist as +2 oxidation state i.e iron have larger size due to which…

Q: An oligosaccharide isolated from an organism is found tocontain two glucose residues and one…

A: Oligosaccharides are short chains of monosaccharides joined by glycosidic bonds. Glycosidic bonds…

Q: Which D-aldopentose is oxidized to an optically active aldaric acid and undergoes the Wohl…

A: The oxidation of D-aldopentose to an optically active aldaric acid is given below.

Q: An unknown carbohydrate of formula C12H22O11 reacts with Tollens reagent to form asilver mirror. An…

A:

Q: The disaccharide lactulose consists of a d-galactopyranose subunit and a d-fructofuranose subunit…

A:

Q: Draw a thipepnice at physidaical PH 7 (PH-7 Comaining alanine, serine ánd aspamo ocid. Draw at each…

A: Aminoacid has a carbon bonded to an amino group a carboxyl group, a hydrogen atom and a R side chain…

Q: complete synthesis of  Tamiflu or Oseltamivir

A: Tamiflu is an antiviral medicine that blocks the action of influenza virus. Tamiflu is also known as…

Q: Thymine is one of the heterocyclic bases found in DNA. Do you expect thymine to bearomatic? Explain

A: The structure of thymine is represented as follows:

Q: A polypeptide was subjected to the following treatments with the indicated results. What is its…

A: Peptides are long chain molecules which are formed by making peptide bond between amino acids. The…

Q: The a-dextro-glucopyranose can be converted to a- levo-glucopyranose by racemase. True False

A:

Q: In acidic solutions, nucleosides are hydrolyzed to a sugar and a heterocyclic base. Propose a…

A:

Q: s are purified and sequenced. The sequences of th eaves after lysine (K) and arginine (R); cyanogen…

A: Given: Trypsin peptides and Cyanogen bromide peptides has given.

Q: Examine all the Haworth structures and check all that applies. Wrong combination of letters are…

A: The sugars with aldehyde(CHO) functional group are called as aldoses. The six carbon aldoses are…

Q: Penicillin makes a covalent bond at the transpeptidase active site (which bond is it?) Why is it not…

A: According to Q&A guidelines of Bartleby, we are supposed to answer only the first question out…

Q: Which of the following C-terminal peptide bonds is more readily cleaved by carboxypeptidase A?…

A: Carboxypeptidase A enzyme is a proteolytic enzyme (exopeptidase) that attacks the peptide bond at…

Q: If anisole is allowed to sit in D2O that contains a small amount of D2SO4, what products are formed?

A: Structure of anisole is as follows, The compound anisole is an organic compound that is colorless…

Q: Draw a mechanism for the hydrolysis of the peptide bond in aspartame. Show arrow pushing

A:

Q: Single hydrolysis on the following polypeptide

A: "Since you have asked multiple questions, we will solve the first question for you. If you want any…

Q: Show how valine can be prepared by a. a Hell–Volhard–Zelinski reaction.  b. a Strecker synthesis.…

A: “Hello. Since you have posted a question with multiple sub-parts, we will solve the first three…

Q: Propose a synthesis for the peptide leu-lys-cys

A: Detail synthetic route is given below

Q: Please propose a method to synthesize the following peptide.  Leu.Gly.Ala  (automated synthesis…

A:

Q: Which D-aldopentose is oxidized to an optically active aldaric acid and undergoes the Wohl…

A: The structure of possible optically active aldaric acid from D-aldopentose are,

Q: Based on the peptide YDCM, which residues are determined via Sanger degradation? Y only M only D and…

A: Sanger degradation determines the N-terminal residue. In this method, peptide chain is treated with…

Q: D-Aldopentose A is oxidized to an optically inactive aldaric acid. On Wohl degradation, A forms an…

A: Wohl degradation is a method which is used for the contraction of the carbon chains in aldose. In…

Q: Show that Ruff degradation of d-mannose gives the same aldopentose (d-arabinose) asdoes d-glucose

A: The Ruff degradation of D-glucose is given below - In the above figure, ruff degradation of…

Q: Show how aspartame can be synthesized using DCCD.

A:

Q: drug synthesis from Pauson khand-reaction

A: The Pauson-Khand reaction is used for the synthesis of cyclopentenones and bicyclic enones.

Q: Show how you could us the acetamidomalonate method to prepare the followig amino acids (a)Leucine…

A: Explanation Amino acids Amino (NH2) and acid (COOH) groups having compounds are called amino acids

Q: (b) Define example for each : the following and provide (i) Chromophore and auxochrome (i) Red shift…

A:

Q: Glucose is an aldose sugar but it does not react with sodium hydrogensulphite. Give reason.

A: Aldose sugar: The carbohydrates that have aldehyde group (-CHO) are called as "Aldose sugars".…

Q: Propose a mechanism for the formation of Melmac.

A: Melmac is a polymer which is formed by the polymerisation of monomers melamine and CH2O

Q: draw the structures from a trypsin-catalysed reaction of Ala-Lys-Ser

A:

Q: -H

A:

Q: Nucleosides are stable in water and in dilute base. In dilute acid, however, the glycosidic bond of…

A: Recall that nucleoside is obtained by forming glucosidic bond between anomeric carbon (C1) of…

Q: RNAase, the enzyme that catalyzes the hydrolysis of RNA, has two catalytically active histidine…

A: Mechanism for RNAase: In the first step of the reaction, the imidazole ring of one histidine acts…

Q: Draw an electron pushing mechanism for proline racemization. Draw a reaction coordinate diagram of…

A:

Q: Pralidoxime is an antidote to organophosphate poisoning. Which of the following is false? N-OH O It…

A: Pralidoxime belongs to family of compounds called oximes that binds to organophosphate -inactivated…

Q: 2. Draw the complete mechanism using arrows showing the movement of electrons for HIV Protease…

A:

Q: Why is peptide synthesis carried out from C terminus to N terminus using dicyclohexylcarbodiimide…

A:

Q: (a) An aliphatic aminoglycoside is relatively stable to base, but it is quickly hydrolyzed bydilute…

A: SOLUTION: Step 1: The reaction of an aliphatic aminoglycosides with water in acidic medium is as…

Q: (d) Draw the cyclic beta form of structure I. (e) Identify the hemiacetal in cyclic beta form of…

A: Note: According to our guidelines we are supposed to answer only first three subpart. Kindly repost…

Q: Draw the expected major product for sequence MCPBA

A:

Q: How to show the cyclization of frontalin

A: The reaction through which a compound is converted to an aromatic compound through several steps is…

Q: Devise a synthesis of threonine from diethyl acetamidomalonate.

A: The diethyl acetamidomalonate gets deprotonated when treated with sodium ethoxide to form an enolate…

Vitamins and Coenzymes

A class of organic compounds needed in the human body for normal activities is known as vitamins. They are characterized into two parts depending upon their solubility in water. They can act as coenzymes, cofactors, or prosthetic groups for enzymes.