Biochemistry: The Molecular Basis of Life
6th Edition
ISBN: 9780190209896
Author: Trudy McKee, James R. McKee
Publisher: Oxford University Press
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Chapter 1, Problem 9RQ
Summary Introduction
To review:
Definition of the following biological terminologies:
(a) mRNA
(b) tRNA
(c) rRNA
(d) siRNA
(e) miRNA
Introduction:
Ribonucleic acid (RNA) is the
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The genome’s functional gene products are either _____________ or _____________.
The eukaryotic mRNA is protected from degradation by a 3′ _____________.
Question 2:
Part a: Complete the table describing different components of intron removal from mRNA. Nu:, X and Y refer to B-type chemistry shown on the previous page. (YELLOW table shown)
Part b: Complete the table describing different components of group I self-splicing intron removal from 26S rRNA in Tetrahymena. (BLUE table shown)
Part c: Draw the intron with an all atom structure for Branchpoint A after intron removal from mRNA
Part d: Draw the Group I self-splicing intron with an all atom structure for the Guanosine cofactor after intron removal from 26S rRNA in Tetrahymena.
Chapter 1 Solutions
Biochemistry: The Molecular Basis of Life
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- A base change that has no discernible effect is called a____________________ mutation.arrow_forwardSuppose the codon sequence GUGCAAUUCGAGGCC has a single base pair mutation to GUGCAAUUCAAGGCC. If the old protein sequence was Val-Gln-Phe-Glu-Ala, what will be the new sequence encoded by the mutant gene? ____________________________.arrow_forwardQuestion 1. Enzymes, proteins and deoxyribonucleic acid (DNA) macromolecules. Enzymes are not only speed up the reaction, but also are necessary for DNA repreduction. are important biological a) Compare the process of protein synthesis between eukaryote mRNA and viral RNA b) With the aid of a diagram, draw an adapter molecule that recognizes the codons of mRNA and explain its functions in DNA translation.arrow_forward
- Expressed sequences of DNA are called ________________.arrow_forwardNoncoding DNA sequences are called __________________.arrow_forwardWhat is unusual about the answers for Questions 13k, 13l, 13m, and 13n? Because the multiple codons exist for most amino acids, the genetic code is said to be _____________.arrow_forward
- _____________ are the linear sequences of nucleotides in an organism’s genetic information.arrow_forwardA _____________________ is a multienzyme complex thatsynthesizes RNA primers during E. coli DNA replication.arrow_forwardQUESTION 15 TRNA: a. can be drawn as a cloverleaf structure b. Has an anticodon C. has modified bases d. all of the abovearrow_forward
- Question 45 When TRNAS and rRNAs have bases that H-bonds with other bases far apart from each other, the RNA molecules assume its secondary and tertiary structure. A) True B) Falsearrow_forwardIf Adenine was added where Guanine should have been added, this would be an example of a ___________________ mutation.arrow_forwardQuestion 47 (a) Use the following figure to determine the changes to the amino acids that correspond to the normal and mutated DNA sequences. Normal DNA sequence: 3 CAT TCA AAC ATT 5 Mutated DNA sequence: 3 CAT AGT GAG GTC 5 (Hint: Write the mRNA first, then identify the amino acids.) (b) What type of mutation is shown? First base of codon U C A G U UUU UUC UUA UUG CUU CUC CUA CUG AUU AUC AUA AUG GUU GUC GUA GUG UCU UCC UCA UCG CCU CCC CCA CCG ACU ACC ACA Met ACG GCU GCC GCA GCG Phe -Leu Leu lle Second base of codon A C Val -Ser Pro Thr Ala UAUTYT туг UAC UAA UAG CAU CAC CAA CAG. His Gin AAU AAC Asn AAA GAUT GAC GAA GAG Asp G AAGLYS AGG. GGU GGC GGA GGG Glu UGU UGC UGA UGG CGU CGC CGA CGG Bys A Trp G U C -Arg AGU AGC AGA аса за Ser Arg U C Gly AG A U C A G U C A G Third base of codonarrow_forward
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